Ruth Sonntag Nussenzweig

Ruth Sonntag Nussenzweig (born 20 June 1928) was the C.V. Starr Professor of Medical And Molecular Parasitology at NYU, a specialist in the development of Malaria vaccines. She is now Research Professor, in NYU's Department of Pathology and Professor Emerita of Microbiology and Pathology, in NYU's Department of Microbiology.

Biography

Nussenzweig received a M.D from University of São Paulo, School of Medicine, São Paulo, Brazil,[1]

In 1967 she demonstrated that mice could acquire immunity to the Plasmodium berghei parasite by exposing them to sporozoites that had been inactivated by irradiated by x-rays.[2]

Major recent publications

Huang, Jing; Li, Xiangming; Coelho-Dos-Reis, Jordana G A; Zhang, Min; Mitchell, Robert; Nogueira, Raquel Tayar; Tsao, Tiffany; Noe, Amy R; Ayala, Ramses; Sahi, Vincent; Gutierrez, Gabriel M; Nussenzweig, Victor; Wilson, James M; Nardin, Elizabeth H; Nussenzweig, Ruth S; Tsuji, Moriya. "Human immune system mice immunized with Plasmodium falciparum circumsporozoite protein induce protective human humoral immunity against malaria." Journal of Immunological Methods. 2015 Sep;:42-50

Teixeira, Lais H; Tararam, Cibele A; Lasaro, Marcio O; Camacho, Ariane G A; Ersching, Jonatan; Leal, Monica T; Herrera, Socrates; Bruna-Romero, Oscar; Soares, Irene S; Nussenzweig, Ruth S; Ertl, Hildegund C J; Nussenzweig, Victor; Rodrigues, Mauricio M. "Immunogenicity of a Prime-Boost Vaccine Containing the Circumsporozoite Proteins of Plasmodium vivax in Rodents. Infection & Immunity. 2014 Feb;82(2):793-807

Mishra, Satish; Nussenzweig, Ruth S; Nussenzweig, Victor. "Antibodies to Plasmodium circumsporozoite protein (CSP) inhibit sporozoite's cell traversal activity." Journal of Immunological Methods. 2012 Mar;377(1-2):47-52

Camacho, Ariane Guglielmi Ariza; Teixeira, Lais Helena; Bargieri, Daniel Youssef; Boscardin, Silvia Beatriz; Soares, Irene da Silva; Nussenzweig, Ruth Sonntag; Nussenzweig, Victor; Rodrigues, Mauricio Martins. "TLR5-dependent immunogenicity of a recombinant fusion protein containing an immunodominant epitope of malarial circumsporozoite protein and the FliC flagellin of Salmonella Typhimurium." Memorias do Instituto Oswaldo Cruz. 2011 Aug;106 Suppl 1:167-171

Mishra, Satish; Rai, Urvashi; Shiratsuchi, Takayuki; Li, Xiangming; Vanloubbeeck, Yannick; Cohen, Joe; Nussenzweig, Ruth S; Winzeler, Elizabeth A; Tsuji, Moriya; Nussenzweig, Victor. "Identification of non-CSP antigens bearing CD8 epitopes in mice immunized with irradiated sporozoites." Vaccine. 2011 Oct 6;29(43):7335-7342

Awards

References

  1. ↑ NYU faculty page
  2. ↑ Nussenzweig, Ruth; J. Vanderberg; H. Most; C. Orton (14 October 1967). "Protective Immunity produced by the Injection of X-irradiated Sporozoites of Plasmodium berghei". Nature. 216 (5111): 160–162. doi:10.1038/216160a0. PMID 6057225. Retrieved 2016-03-03.
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