Iotalamic acid

Iotalamic acid
Clinical data


AHFS/Drugs.com	International Drug Names
ATC code	V08AA04 (WHO)
Identifiers
IUPAC name 3-acetamido-2,4,6-triiodo-5-(methylcarbamoyl)benzoic acid
PubChem (CID)	3737
ChemSpider	3606
UNII	16CHD79MIX^Y
KEGG	D01258
ECHA InfoCard	100.017.181
Chemical and physical data
Formula	C₁₁H₉I₃N₂O₄
Molar mass	613.91357
3D model (Jmol)	Interactive image
SMILES CC(=O)NC1=C(C(=C(C(=C1I)C(=O)O)I)C(=O)NC)I
InChI InChI=1S/C11H9I3N2O4/c1-3(17)16-9-7(13)4(10(18)15-2)6(12)5(8(9)14)11(19)20/h1-2H3,(H,15,18)(H,16,17)(H,19,20) Key:UXIGWFXRQKWHHA-UHFFFAOYSA-N

Iotalamic acid (also iothalamic acid in USAN) and its salts (INN Iothalamates) is an iodine-containing organic anion used as a radiocontrast agent. It is available as sodium iothalamate (Iothalamate sodium) and meglumine iothalamate (Iothalmate meglumine). It can be administered intravenously or intravesically (into the urinary bladder).^[1]

Radioactive formulation is also available as sodium iothalamate I-125 Injection (GLOFIL-125). It is indicated for evaluation of glomerular filtration in the diagnosis or monitoring of patients with renal disease.^[1]

References

1 2 "Iothalamate Meglumine and Iothalamate Sodium Drug Information, Professional". www.drugs.com. Retrieved 2016-07-16.

Contrast media (V08)

X-ray and CT

Iodinated,
Water soluble

Nephrotropic, high osmolar	Diatrizoic acid^# Metrizoic acid Iodamide Iotalamic acid Ioxitalamic acid Ioglicic acid Acetrizoic acid Iocarmic acid Methiodal Diodone

Nephrotropic, low osmolar	Metrizamide Iohexol^# Ioxaglic acid Iopamidol Iopromide Iotrolan Ioversol Iopentol Iodixanol Iomeprol Iobitridol Ioxilan

Hepatotropic	Iodoxamic acid Iotroxic acid Ioglycamic acid Adipiodone Iobenzamic acid Iopanoic acid Iocetamic acid Sodium iopodate Tyropanoic acid Calcium iopodate

Iodinated,
Water insoluble

Non-iodinated

Barium sulfate^#

MRI

Paramagnetic	Gadolinium-based: Gadobenic acid Gadobutrol Gadodiamide Gadofosveset Gadolinium Gadopentetic acid Gadoteric acid Gadoteridol Gadoversetamide Gadoxetic acid Other: Ferric ammonium citrate Mangafodipir

Superparamagnetic	Ferumoxsil Ferristene Iron oxide, nanoparticles

Other	Perflubron

Ultrasound

^#WHO-EM
^‡Withdrawn from market
Clinical trials:
- ^†Phase III
- ^§Never to phase III

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