Perflenapent
 | |
 | |
| Names | |
|---|---|
| Preferred IUPAC name
Dodecafluoropentane | |
| Other names
Perfluoropentane (no longer recommended[1]) | |
| Identifiers | |
| 678-26-2 | |
| 3D model (Jmol) | Interactive image |
| ChemSpider | 12154 |
| ECHA InfoCard | 100.010.589 |
| PubChem | 12675 |
| |
| |
| Properties | |
| C5F12 | |
| Molar mass | 288.04 g·mol−1 |
| Density | 1.63 g/mL (liquid, 25 °C) [2] 1.59 g/mL (liquid, 35 °C) |
| Melting point | −115 °C (−175 °F; 158 K) |
| Boiling point | 28 °C (82 °F; 301 K) |
| Vapor pressure | 83.99 kPa (25 °C) |
| Viscosity | 0.652 mPa*s (25 °C) |
| Thermochemistry | |
| 0.26 cal/(g • K) | |
| Pharmacology | |
| V08DA03 (WHO) | |
| Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). | |
| Infobox references | |
Perflenapent (INN/USAN), or perfluoropentane (PFP), is a fluorocarbon. It has several biomedical applications including: propellant for pressurized metered dose inhalers;[3] gas core in microbubble ultrasound contrast agents;[4] and occlusion therapy via the conversion of nanometer liquid droplets into micrometer sized gas microbubbles (acoustic droplet vaporization).[5]
References
- ↑ Nomenclature of Organic Chemistry : IUPAC Recommendations and Preferred Names 2013 (Blue Book). Cambridge: The Royal Society of Chemistry. 2014. p. 33. doi:10.1039/9781849733069-FP001. ISBN 978-0-85404-182-4.
The prefix ‘per-’ is no longer recommended.
- ↑ "Perfluoropentane". Retrieved January 14, 2013.
- ↑ Rogueda, P. G. A. HPFP, a Model Propellant for pMDIs. Drug Dev. Ind. Phar. 2003, 29, 39
- ↑ Liu, Y., Miyoshi, H., and Nakamura, M. Encapsulated ultrasound microbubbles: Therapeutic application in drug/gene delivery. J. Controlled Release 2006, 114, 89− 99
- ↑ D. Bardin, T. D. Martz, P. S. Sheeran, R. Shih, P. A. Dayton, and A. P. Lee, “High-speed, clinical-scale microfluidic generation of stable phase-change droplets for gas embolotherapy,” Lab on a Chip, vol. 11, no. 23, p. 3990, 2011.
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