Ciliary body melanoma
Ciliary Body Melanoma is a type of cancer arising from the coloured part (uvea) of the eye.
About 12% of uveal melanoma arise from the ciliary body.
Clinical features
It occurs most commonly in the sixth decade.
- External signs include dilated episcleral blood vessels (sentinel vessels). Extraocular erosion may produce a dark mass beneath the conjunctiva.
- Pressure on the lens by the enlarging tumor can cause astigmatism, sublaxtion of the lens and formation of a localised lens opacity.
- The tumor can erode forward through the iris root and mimic an iris melanoma.
- Retinal detachment can be rarely caused by posterior extension of the tumor.
- Anterior uveitis is an uncommon presentation and occurs due to tumor necrosis.
- Cirumferentially growing tumors carry a bad prognosis as they are diagnosed late.
- At times the tumor is detected as an incidental finding during routine examination.
The tumour is usually diagnosed by clinical examination with a slit-lamp utilising a triple mirror contact lens. Ultrasonography and fine needle aspiration biopsy (FNAB) are also sometimes helpful in confirming the diagnosis.
Treatment
Enucleation (surgical removal of the eye) is the treatment of choice for large ciliary body melanomas. Small or medium sized tumors may be treated by an iridocyclectomy. Radiotherapy may be appropriate in selected cases.
See also
- Ocular oncology
- Uveal melanoma - melanoma of the eye
References
- Ciliary Body Melanoma - Springer
- Redirecting
- Microvascular Density in Predicting Survival of Patients with Choroidal and Ciliary Body Melanoma
- Long-term risk of local failure after proton therapy for choroidal/ciliary body melanoma
- Redirecting
- Matched group study of surgical resection versus cobalt-60 plaque radiotherapy for primary... - Abstract - Europe PubMed Central
External links
This article is issued from Wikipedia - version of the 10/8/2016. The text is available under the Creative Commons Attribution/Share Alike but additional terms may apply for the media files.