Envelysin

Envelysin
Identifiers
EC number 3.4.24.12
CAS number 50812-13-0
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum

Envelysin (EC 3.4.24.12, sea-urchin-hatching proteinase, hatching enzyme, chorionase, chorion-digesting proteinase, chymostrypsin, sea urchin embryo hatching enzyme) is an enzyme.[1][2][3][4] This enzyme catalyses the following chemical reaction

Hydrolysis of proteins of the fertilization envelope and dimethylcasein

This enzyme is a glycoprotein from various members of the class Echinoidea.

References

  1. Barrett, D.; Edwards, B.F. (1976). "Hatching enzyme of the sea urchin Strongylocentrotus purpuratus". Methods Enzymol. 45: 354–373. doi:10.1016/s0076-6879(76)45032-2. PMID 1012003.
  2. Lepage, T.; Gache, C. (1989). "Purification and characterization of the sea urchin embryo hatching enzyme". J. Biol. Chem. 264: 4787–4793. PMID 2925668.
  3. Lepage, T.; Gache, C. (1990). "Early expression of a collagenase-like hatching enzyme gene in the sea urchin embryo". EMBO J. 9: 3003–3012. PMID 2167841.
  4. Nomura, K.; Tanaka, H.; Kikkawa, Y.; Yamaguchi, M.; Suzuki, N. (1991). "The specificity of sea urchin hatching enzyme (envelysin) places it in the mammalian matrix metalloproteinase family". Biochemistry. 30: 6115–6123. doi:10.1021/bi00239a005. PMID 1711895.

External links

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