Weisz is a surname. Notable people with the surname include:
- Berthold Weisz (born 1845), Hungarian deputy
- Erik Weisz (1874-1926), Hungarian-born American magician best known by the stage name "Harry Houdini"
- Ezra Weisz (born 1971), American voice actor
- Franziska Weisz (born 1980), Austrian actress
- Rachel Weisz (born 1971), English American actress
- Victor Weisz (1913–1966), German-British political cartoonist
- Zoni Weisz (born 1937), Dutch Porajmos survivor