|Warren C. W. Chan|
|Fields||Biomedical Engineering, Nanotechnology|
|Institutions||University of Toronto|
University of Illinois|
|Doctoral advisor||Shuming Nie|
Quantum dots for biology|
Kabiller Young Investigator Award (2015)|
NSERC E. W. R. Memorial Steacie Fellowship (2013)
International Dennis Gabor Award (2009)
Lord Rank Prize Fund (2006)
BF Goodrich Young Inventors Award (1999)
Professor Warren Chan is currently a full professor at the Institute of Biomaterials and Biomedical Engineering and Terrence Donnelly Centre for Cellular and Biomolecular Research at the University of Toronto. He received his B.S. and PhD degree, and post-doctoral training from the University of Illinois, Indiana University, and University of California, San Diego.
His research lab is focused on the development of nanoparticles for diagnosing and treating cancer and infectious diseases. Some of the contributions he has made to science and engineering has been (a) the development of quantum dots for biomedical applications, (b) the size and shape dependent cellular interactions of nanoparticles in vitro and in vivo, (c) the identification of the protein corona on nanoparticle and its effect on cancer targeting, and (d) the development of a smartphone-based point of care device for diagnosing infected patients. For his research, he has won many Canadian and International Awards (e.g., NSERC Steacie Fellowship (Canada), International Dennis Gabor Award (Hungary), Rank Prize Fund (UK), and BF Goodrich Young Inventors Award (USA)).
He is currently an Associate Editor of ACS Nano.
- , S. D. Perrault, C. Walkey, T. Jennings, H.C. Fischer, W. C. W. Chan, "Mediating Tumor Targeting Efficiency of Nanoparticles through Design," Nano Letters, 2009, 9, 1905.,
- , W. Jiang, B. Y. Kim, J. T. Rutka, W.C.W. Chan, "Nanoparticle-Mediated Cellular Response is Size Dependent," Nature Nanotechnology, 2008, 3, 145.
- , J. M. Klostranec, Q. Xiang, G. A. Farcas, J. A. Lee, A. Rhee, E. I. Lafferty, S. D. Perrault, K. C. Kain, W. C. W. Chan, "Convergence of Quantum Dot Barcodes with Microfluidics and Signal Processing for Multiplexed High-Throughput Infectious Disease Diagnostics," Nano Letters 2007, 7, 2812..
- , A. Ghazani, J. A. Lee, J. Klostranec, Q. Xiang, R. Da Costa, B. C. Wilson, M. Tsao, W.C.W. Chan, "High Throughput Quantification of Protein Expression of Cancer Antigens in Tissue Microarray using Quantum Dot Nanocrystals," Nano Letters, 2006, 6, 2881. Highlighted in Science (2006, 314, 1661).
- , H. Fischer, L. Li, K.S. Pang and W.C.W. Chan, "Pharmacokinetics of Nanoscale Quantum Dots: In Vivo Distribution, Sequestration, and Clearance in Rats," Advanced Functional Materials, 2006, 16, 1299.