UTY (gene)

UTY
Available structures
PDBHuman UniProt search: PDBe RCSB
Identifiers
Aliases UTY, KDM6AL, UTY1, ubiquitously transcribed tetratricopeptide repeat containing, Y-linked
External IDs GeneCards: UTY
RNA expression pattern




More reference expression data
Orthologs
Species Human Mouse
Entrez

7404

n/a

Ensembl

ENSG00000183878

n/a

UniProt

O14607

n/a

RefSeq (mRNA)

n/a

RefSeq (protein)

n/a

Location (UCSC) Chr Y: 13.25 – 13.48 Mb n/a
PubMed search [1] n/a
Wikidata
View/Edit Human

Histone demethylase UTY is an enzyme that in humans is encoded by the UTY gene.[2][3][4]

This gene encodes a protein containing tetratricopeptide repeats which are thought to be involved in protein-protein interactions. This protein is a minor histocompatibility antigen which may induce graft rejection of male stem cell grafts. Alternative splicing results in multiple transcript variants encoding different isoforms.[4]

Interactions

UTY (gene) has been shown to interact with TLE1,[5] and WDR90[6]

References

  1. "Human PubMed Reference:".
  2. Greenfield A, Scott D, Pennisi D, Ehrmann I, Ellis P, Cooper L, Simpson E, Koopman P (Jan 1997). "An H-YDb epitope is encoded by a novel mouse Y chromosome gene". Nat Genet. 14 (4): 474–478. doi:10.1038/ng1296-474. PMID 8944031.
  3. Greenfield A, Carrel L, Pennisi D, Philippe C, Quaderi N, Siggers P, Steiner K, Tam PP, Monaco AP, Willard HF, Koopman P (May 1998). "The UTX gene escapes X inactivation in mice and humans". Hum Mol Genet. 7 (4): 737–742. doi:10.1093/hmg/7.4.737. PMID 9499428.
  4. 1 2 "Entrez Gene: UTY ubiquitously transcribed tetratricopeptide repeat gene, Y-linked".
  5. Grbavec, D; Lo R; Liu Y; Greenfield A; Stifani S (Jan 1999). "Groucho/transducin-like enhancer of split (TLE) family members interact with the yeast transcriptional co-repressor SSN6 and mammalian SSN6-related proteins: implications for evolutionary conservation of transcription repression mechanisms". Biochem. J. ENGLAND. 337 (1): 13–7. doi:10.1042/0264-6021:3370013. ISSN 0264-6021. PMC 1219929Freely accessible. PMID 9854018.
  6. "STRING: functional protein association networks". string-db.org. Retrieved 2015-05-07.

Further reading


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