UQCRQ
| UQCRQ | ||||||
|---|---|---|---|---|---|---|
| Identifiers | ||||||
| Aliases | UQCRQ, MC3DN4, QCR8, QP-C, QPC, UQCR7, ubiquinol-cytochrome c reductase complex III subunit VII | |||||
| External IDs | MGI: 107807 HomoloGene: 40942 GeneCards: UQCRQ | |||||
| Orthologs | ||||||
| Species | Human | Mouse | ||||
| Entrez | ||||||
| Ensembl | ||||||
| UniProt | ||||||
| RefSeq (mRNA) | ||||||
| RefSeq (protein) | ||||||
| Location (UCSC) | Chr 5: 132.87 – 132.87 Mb | Chr 11: 53.43 – 53.43 Mb | ||||
| PubMed search | [1] | [2] | ||||
| Wikidata | ||||||
| View/Edit Human | View/Edit Mouse |
Ubiquinol-cytochrome c reductase, complex III subunit VII, 9.5kDa is a protein that in humans is encoded by the UQCRQ gene.[3]
Function
This gene encodes a ubiquinone-binding protein of low molecular mass. This protein is a small core-associated protein and a subunit of ubiquinol-cytochrome c reductase complex III, which is part of the mitochondrial respiratory chain.
References
Further reading
- Schägger H, Brandt U, Gencic S, von Jagow G (1995). "Ubiquinol-cytochrome-c reductase from human and bovine mitochondria". Methods in Enzymology. 260: 82–96. doi:10.1016/0076-6879(95)60132-5. PMID 8592474.
- Barel O, Shorer Z, Flusser H, Ofir R, Narkis G, Finer G, Shalev H, Nasasra A, Saada A, Birk OS (May 2008). "Mitochondrial complex III deficiency associated with a homozygous mutation in UQCRQ". American Journal of Human Genetics. 82 (5): 1211–6. doi:10.1016/j.ajhg.2008.03.020. PMC 2427202
. PMID 18439546. - Wen JJ, Garg N (Dec 2004). "Oxidative modification of mitochondrial respiratory complexes in response to the stress of Trypanosoma cruzi infection". Free Radical Biology & Medicine. 37 (12): 2072–81. doi:10.1016/j.freeradbiomed.2004.09.011. PMID 15544925.
- Sifroni KG, Damiani CR, Stoffel C, Cardoso MR, Ferreira GK, Jeremias IC, Rezin GT, Scaini G, Schuck PF, Dal-Pizzol F, Streck EL (Sep 2010). "Mitochondrial respiratory chain in the colonic mucosal of patients with ulcerative colitis". Molecular and Cellular Biochemistry. 342 (1-2): 111–5. doi:10.1007/s11010-010-0474-x. PMID 20440543.
- Usui S, Yu L, Yu CA (May 1990). "The small molecular mass ubiquinone-binding protein (QPc-9.5 kDa) in mitochondrial ubiquinol-cytochrome c reductase: isolation, ubiquinone-binding domain, and immunoinhibition". Biochemistry. 29 (19): 4618–26. doi:10.1021/bi00471a017. PMID 2164842.
This article incorporates text from the United States National Library of Medicine, which is in the public domain.
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