Tropic acid

Tropic acid
Names

IUPAC name 3-Hydroxy-2-phenylpropanoic acid
Other names 2-Phenylhydracrylic acid; Tropate
Identifiers
CAS Number	529-64-6^Y
3D model (Jmol)	Interactive image
ChEBI	CHEBI:CHEBI:30765^N
ChemSpider	10274^N
ECHA InfoCard	100.007.697
EC Number	209-020-6
KEGG	C01456^N
MeSH	C011377
PubChem	10726
InChI InChI=1S/C9H10O3/c10-6-8(9(11)12)7-4-2-1-3-5-7/h1-5,8,10H,6H2,(H,11,12)^N Key: JACRWUWPXAESPB-UHFFFAOYSA-N^N InChI=1/C9H10O3/c10-6-8(9(11)12)7-4-2-1-3-5-7/h1-5,8,10H,6H2,(H,11,12) Key: JACRWUWPXAESPB-UHFFFAOYAV
SMILES C1=CC=C(C=C1)C(CO)C(=O)O
Properties
Chemical formula	C₉H₁₀O₃
Molar mass	166.18 g·mol⁻¹
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
N verify (what is ^YN ?)
Infobox references

Tropic acid is a chemical with IUPAC name 3-hydroxy-2-phenylpropanoic acid and condensed structural formula HOCH₂CHPhCOOH. It is a laboratory reagent used in the chemical synthesis of atropine and hyoscyamine. Tropic acid is a chiral substance, existing as either a racemic mixture or as a single enantiomer.

Synthesis

Tropic acid synthesis 1:^[1]	Tropic acid synthesis 2:^[1]

Prepn:^[2]^[3]^[4]

References

1 2 Gadzikowska, M; Grynkiewicz, G (2002). "Tropane alkaloical and phytochemical analysis". Acta poloniae pharmaceutica. 59 (2): 149–60. PMID 12365608.
↑ Sletzinger, Paulsen, U.S. Patent 2,390,278 (1945 to Merck & Co.).
↑ Blicke, U.S. Patent 2,716,650 (1955 to University of Michigan).
↑ DE 923426 (1955 to Sterling Drug).

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