Supramolecular chirality

In chemistry, the term supramolecular chirality is used to describe supramolecular assemblies that are non-superposable on their mirror images.

Chirality in supramolecular chemistry implies the non-symmetric arrangement of molecular components in a non-covalent assembly. Chirality may arise in a supramolecular system if one of its component is chiral or if achiral components arrange in a non symmetrical way to produce a supermolecule that is chiral. Important examples of the latter case have been reported by Jean-Marie Lehn.

References

^ Supramolecular Chirality: Chiral hydrogen-bonded supermolecules from achiral molecular components Suárez M, Branda N, Lehn JM, Decian A, Fischer J, Helvetica Chimica Acta 1998 81 1-13.

Concepts in asymmetric synthesis

Chirality types	Chirality Stereocenter Planar chirality Chiral ligand Axial chirality Supramolecular chirality Inherent chirality

Chiral molecules	Stereoisomer Enantiomer Diastereomer meso compound racemic mixture Enantiomeric excess (ee) Diastereomeric excess (de)

Analysis	Optical rotation Chiral derivatizing agents NMR spectroscopy of stereoisomers Ultraviolet-visible spectroscopy of stereoisomers

Chiral resolution	Recrystallization Kinetic resolution Chiral column chromatography Diastereomeric recrystallization

Reactions	Asymmetric induction Chiral pool synthesis Chiral auxiliaries Asymmetric catalysis Organocatalysis Biocatalysis

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