Streptogrisin A

Streptogrisin A
Identifiers
EC number 3.4.21.80
CAS number 55326-50-6
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum

Streptogrisin A (EC 3.4.21.80, Streptomyces griseus protease A, protease A, proteinase A, Streptomyces griseus proteinase A, Streptomyces griseus serine proteinase 3, Streptomyces griseus serine proteinase A) is an enzyme.[1][2][3][4][5] This enzyme catalyses the following chemical reaction

Hydrolysis of proteins with specificity similar to chymotrypsin

This enzyme is isolated from Streptomyces griseus.

References

  1. Johnson, P.; Smillie, L.B. (1971). "The disulfide bridge sequences of a serine protease of wide specificity from Streptomyces griseus". Can. J. Biochem. 49: 548–562. doi:10.1139/o71-082. PMID 5575653.
  2. Sielecki, A.R.; Hendrickson, W.A.; Broughton, C.G.; Delbaere, L.T.J.; Brayer, G.D.; James, M.N.G. (1979). "Protein structure refinement: Streptomyces griseus serine protease A at 1.8 Å resolution". J. Mol. Biol. 134: 781–804. doi:10.1016/0022-2836(79)90486-8. PMID 119870.
  3. James, M.N.G.; Sielecki, A.R.; Brayer, G.D.; Delbaere, L.T.J.; Bauer, C.-A. (1980). "Structures of product and inhibitor complexes of Streptomyces griseus protease A at 1.8 Å resolution". J. Mol. Biol. 144: 43–88. doi:10.1016/0022-2836(80)90214-4. PMID 6783761.
  4. Delbaere, L.T.J.; Brayer, G.D. (1985). "The 1.8 Å structure of the complex between chymostatin and Streptomyces griseus protease A. A model for serine protease catalytic tetrahedral intermediates". J. Mol. Biol. 183: 89–103. doi:10.1016/0022-2836(85)90283-9. PMID 3892018.
  5. Henderson, G.; Krygsman, P.; Liu, C.J.; Davey, C.C.; Malek, L.T. (1987). "Characterization and structure of genes for proteases A and B from Streptomyces griseus". J. Bacteriol. 169: 3778–3784. PMID 3112129.
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