Sereno, Missouri

Sereno, Missouri
unincorporated community

Location of Perry County, Missouri
Coordinates: 37°47′52″N 89°51′04″W / 37.79778°N 89.85111°W / 37.79778; -89.85111Coordinates: 37°47′52″N 89°51′04″W / 37.79778°N 89.85111°W / 37.79778; -89.85111
Country United States
State Missouri
County Perry
Township Bois Brule
Elevation 620 [1] ft (189 m)
Time zone Central (CST) (UTC-6)
  Summer (DST) CDT (UTC-5)
ZIP code 63775
Area code(s) 573
FIPS code 29-66746 [2]
GNIS feature ID 726210 [3]

Sereno is an unincorporated community located in Bois Brule Township in Perry County, Missouri. Sereno is located about five miles northeast of Perryville, Missouri.


The early settlers of Sereno named the community Serena, meaning “a clean, respectable place”. However, when establishing a post office they discovered a place by that name already existed in Missouri, so the name was changed to Sereno.[4]


In 1884 Thomas Moore gave a small track of his land along Chester Road to William Mattingly for the purpose of building a general store, which was soon followed by a grist mill.[5] A post office operated from 1888-1905.[6] The predominantly Catholic town established Our Lady of Victory Catholic parish in 1908.[7]


  1. Missouri
  2. Hometown Locator: Missouri
  3. Missouri
  4. State Historical Society of Missouri
  5. State Historical Society of Missouri: Perry County Place Names
  6. Missouri Postal History
  7. Archdiocese of St. Louis
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