2-Chlorobenzoic acid
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| Names | |
|---|---|
| IUPAC name
2-chlorobenzoic acid | |
| Other names
o-Chlorobenzoic acid | |
| Identifiers | |
118-91-2  | |
| 3D model (Jmol) | Interactive image |
| ChEBI | CHEBI:30793 |
| ChEMBL | ChEMBL115243 |
| ChemSpider | 8071 |
| ECHA InfoCard | 100.003.897 |
| KEGG | C02357 |
| PubChem | 8374 |
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| Properties | |
| C7H5ClO2 | |
| Molar mass | 156.57 g·mol−1 |
| Appearance | white solid |
| Melting point | 142 °C (288 °F; 415 K) |
| Boiling point | 285 °C (545 °F; 558 K) |
| Hazards | |
| Safety data sheet | Oxford MSDS |
| Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). | |
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| Infobox references | |
2-Chlorobenzoic acid is an organic compound with the formula ClC6H4CO2H. It is one of three isomeric chlorobenzoic acids, the one that is the strongest acid. This white solid is used as a precursor to a variety of drugs, food additives, and dyes.[1]
Synthesis and reactions
It is prepared by the oxidation of 2-chlorotoluene. The laboratory scale reaction employs potassium permanganate.[2] Alternatively it arises by the hydrolysis of α,α,α-trichloro-2-toluene.
The chloride is readily replaced by ammonia to 2-aminobenzoic acid. At elevated temperature is decarboxylates.[1]
References
- 1 2 Takao Maki, Kazuo Takeda "Benzoic Acid and Derivatives" in Ullmann's Encyclopedia of Industrial Chemistry 2002, Wiley-VCH, Weinheim. doi:10.1002/14356007.a03_555.
- ↑ H. T. Clarke and E. R. Taylor (1943). "o-Chlorobenzoic acid". Org. Synth.; Coll. Vol., 2, p. 135
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