Career as government official
- 1381 (Eitoku 1, 7th month): Yoshimoto is made Daijō Daijin.
- 1387 (Kakei 1, 1st month): Yoshimoto is deprived of his position as daijō daijin.
- 1388 (Kakei 2, 6th month): Yoshitomo dies at age 69; and his son Nijō Morotsugu succeeds him with the title of kampaku.
Yoshimoto learned waka from Ton'a and renga from Gusai and Kyūsei. He regarded himself primarily as a waka poet; he authored several treatises on the subject. It is for renga that he is best known. By the age of thirty, he was regarded as an authority on the subject. He authored a number of books including:
- Renri Hishō (連理秘抄 A Secret Treatise of Renga Principles, c. 1349), a text on renga poetics
- Tsukubashū (菟玖波集 The Tsukuba Collection, c. 1356), the first edited collection of renga
- Tsukuba Mondō (筑波問答 The Tsukuba Dialogues, 1357-1372), general discourse on renga in question-answer style
- Gumonkenchū (愚問賢註, 1363), a discussion of renga style; co-authored with Ton'a
- Ōan Shinshiki (応安新式, c. 1372), a text on renga rules
- Kinrai Fūteishō (近来風体抄, 1387), a treatise on waka poetics
The author of Masukagami is unknown, but it is believed that Nijō Yoshimoto had a hand in its writing. The book is a Japanese historical tale describing events understood to have occurred between 1368 and 1376.
His diary, Kuchi-ura, "gives considerable detail" of the Northern Court.
- Titsingh, Isaac. (1834). Annales des empereurs du japon, p. 297.
- Titsingh, p. 316.
- Titsingh, p. 318.
- Miner, Earl Roy. (1980) Japanese Linked Poetry, p. 20.
- Nussbaum, Louis-Frédéric et al. (2005). "Masu-kagami" in Japan Encyclopedia, p. 615.
- Sansom, George (1961). A History of Japan, 1334-1615. Stanford University Press. p. 94. ISBN 0804705259.
- Miner, Earl Roy. (1980). Japanese Linked Poetry: an Account with Translations of Renga and Haikai Sequences. Princeton: Princeton University Press. ISBN 0-691-01368-3; OCLC 19523018
- Horton, H. Mack (1999). Carter, Steven D, ed. "Nijô Yoshimoto". Medieval Japanese Writers. Detroit: The Gale Group: 234–46.
- Nussbaum, Louis Frédéric and Käthe Roth. (2005). Japan Encyclopedia. Cambridge: Harvard University Press. ISBN 978-0-674-01753-5; OCLC 48943301
- Titsingh, Isaac, ed. (1834). [Siyun-sai Rin-siyo/Hayashi Gahō, 1652], Nipon o daï itsi ran; ou, Annales des empereurs du Japon. Paris: Oriental Translation Fund of Great Britain and Ireland. OCLC 84067437
- ネケト. 二条家（摂家） (in Japanese). Retrieved 2007-09-14.