N-acetylgalactosamine-4-sulfatase
| N-acetylgalactosamine-4-sulfatase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 3.1.6.12 | ||||||||
| CAS number | 55354-43-3 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
N-acetylgalactosamine-4-sulfatase (EC 3.1.6.12, chondroitinsulfatase, chondroitinase, arylsulfatase B, acetylgalactosamine 4-sulfatase, N-acetylgalactosamine 4-sulfate sulfohydrolase) is an enzyme with systematic name N-acetyl-D-galactosamine-4-sulfate 4-sulfohydrolase.[1][2][3] This enzyme catalyses the following chemical reaction
- Hydrolysis of the 4-sulfate groups of the N-acetyl-D-galactosamine 4-sulfate units of chondroitin sulfate and dermatan sulfate
This enzazyme also acts on N-acetylglucosamine 4-sulfate.
References
- ↑ Farooqui, A.A. (1976). "The desulphation of hexosamine sulphates by arylsulphatase B". Experientia. 32 (10): 1242–1244. doi:10.1007/BF01953071. PMID 976430.
- ↑ Gorham, S.D.; Cantz, M. (1978). "Arylsulphatase B, an exo-sulphatase for chondroitin 4-sulphate tetrasaccharide". Hoppe-Seyler's Z. Physiol. Chem. 359 (12): 1811–1814. doi:10.1515/bchm2.1978.359.2.1811. PMID 738706.
- ↑ Tsuji, M.; Nakanishi, Y.; Habuchi, H.; Ishihara, K.; Suzuki, S. (1980). "The common identity of UDP-N-acetylgalactosamine 4-sulfatase, nitrocatechol sulfatase (arylsulfatase), and chondroitin 4-sulfatase". Biochim. Biophys. Acta. 612 (2): 373–383. doi:10.1016/0005-2744(80)90120-5. PMID 7370276.
See also
External links
- N-acetylgalactosamine-4-sulfatase at the US National Library of Medicine Medical Subject Headings (MeSH)
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