Louise Brown

For other people named Louise Brown, see Louise Brown (disambiguation).
Louise Joy Brown
Born (1978-07-25) 25 July 1978
Oldham General Hospital, Oldham, England
Known for First in-vitro baby
Weight 5 lb 12 oz (2.608 kg) at birth
Spouse(s) Wesley Mullinder (2004–present)
Children 2 sons, Cameron (born 20 December 2006); Aiden (born August 2013)
Family Lesley and John Brown (parents)
Natalie Brown (sister)

Louise Joy Brown (born 25 July 1978) is an English woman known for being the first human to have been born after conception by in vitro fertilisation, or IVF.


Louise Brown was born at Oldham General Hospital, Oldham, by planned Caesarean section delivered by registrar John Webster.[1] She weighed 5 pounds, 12 ounces (2.608 kg) at birth.[2] Her parents, Lesley and John Brown, had been trying to conceive for nine years. Lesley faced complications of blocked fallopian tubes.[2]

On 10 November 1977, Lesley Brown underwent a procedure, later to become known as IVF (in vitro fertillisation), developed by Patrick Steptoe and Robert Edwards. Edwards was awarded the 2010 Nobel Prize in Medicine for this work.[3] Although the media referred to Brown as a "test tube baby",[4] her conception actually took place in a petri dish. Her younger sister, Natalie Brown, was also conceived through IVF four years later, and became the world's fortieth IVF baby. In May 1999, Natalie was the first IVF baby to give birth herselfwithout IVFto daughter Casey.[2] Natalie has subsequently had three additional children; sons Christopher, Daniel, and Aeron, the last of whom was born in August 2013.[5]

In 2004, Brown married nightclub doorman (bouncer) Wesley Mullinder. Dr. Edwards attended their wedding.[2] Their son Cameron, conceived naturally,[4] was born on 20 December 2006.[6] Brown's second son, Aiden Patrick Robert, was born in August 2013.[5]

Brown's father died in 2007.[7] Her mother died on 6 June 2012 in Bristol Royal Infirmary at the age of 64[8] due to complications from a gallbladder infection.[7]

Ethical and religious issues

Although the Browns knew the procedure was experimental, the doctors did not tell them that no case had yet resulted in a baby. This has raised questions of informed consent.[9]

Shortly before the death of Pope Paul VI, when asked for his reaction to Brown's birth, the patriarch of Venice, Cardinal Albino Luciani (later Pope John Paul I), expressed concerns about the possibility that artificial insemination could lead to women being used as "baby factories", but also refused to condemn the parents of the child,[10] noting they simply wanted to have a baby.[11]


  1. Hutchinson, Martin (24 July 2003). "I helped deliver Louise". BBC News.
  2. 1 2 3 4 "World's first IVF baby marks 30th birthday", Agence France-Presse, 23 July 2008. Retrieved 24 July 2008.
  3. Wade, Nicholas (4 October 2010). "Pioneer of in Vitro Fertilisation Wins Nobel Prize". New York Times. Retrieved 5 October 2010.
  4. 1 2 Hall, Sarah (11 July 2006). "Louise Brown, first test tube baby, is pregnant". The Guardian. London.
  5. 1 2 "World's first test-tube baby pays emotional tribute to her parents for risking global condemnation to have her and pave the way for FIVE MILLION IVF births". Daily Mail. 29 November 2013.
  6. "Baby son joy for test-tube mother". BBC News. 14 January 2007.
  7. 1 2 Denise Grady "Lesley Brown, Mother of World’s First ‘Test-Tube Baby,’ Dies at 64", New York Times, 23 June 2012
  8. "First test tube baby mother Lesley Brown dies", Bristol news, BBC News, 20 June 2012, retrieved 20 June 2012
  9. Robin Marantz Henig, Pandora's Baby, Houghton Mifflin, 2004, p 134
  10. Prospettive nel Mondo,1 August 1978; Luciani, Opera Omnia, vol. 8, pp. 571-72.
  11. Eley, Adam (23 July 2015). "How has IVF developed since the first 'test-tube baby'?". BBC.

External links

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