Károlyi is a Hungarian surname and nobility, and may refer to:
- Károlyi family
- Béla Károlyi (born 1942), Hungarian gymnastics coach
- Márta Károlyi (born 1942), gymnastics coach and National Team Coordinator for USA Gymnastics
- Tibor Károlyi (born 1961), Hungarian chess International Master
There is also a vineyard in Hungary producing white and red wines under the Károlyi appellation.