The clan traces its history from Minamoto no Yoshiie through his son Minamoto Yoshitoki.
They took their name from the Ishikawa district of Kawachi Province. In the Sengoku Period, the family had two major branches; one of them, which had settled in Mikawa Province in the 15th century, was a family of retainers serving what became the Tokugawa clan. Ishikawa Kazumasa, one of Tokugawa Ieyasu's senior retainers, was famous in his era for suddenly leaving Tokugawa service and pledging loyalty to Toyotomi Hideyoshi. However, as Kazumasa's son Yasunaga became implicated in the Ōkubo Yasunaga incident, his branch of the Ishikawa of Mikawa came to an end then. The Mikawa-Ishikawa line continued through Kazumasa's uncle Ienari, Ienari's descendants eventually came to rule the Ise-Kameyama Domain for most of the Edo period.
Select list of clan members
- Ishikawa Yasumichi (1554–1607)
- Ishikawa Tadafusa (1572–1650)
- Ishikawa Kiyokane
- Ishikawa Yasumasa
- Ishikawa Yasunaga
- Ishikawa Kazunori
- Ishikawa Tomoji (1900-1940)
- 石川氏 at Harimaya.com (Japanese)