HTR3C

HTR3C
Identifiers
Aliases HTR3C
External IDs HomoloGene: 50847 GeneCards: HTR3C
Orthologs
Species Human Mouse
Entrez

170572

n/a

Ensembl

ENSG00000178084

n/a

UniProt

Q8WXA8

n/a

RefSeq (mRNA)

NM_130770

n/a

RefSeq (protein)

NP_570126.2

n/a

Location (UCSC) Chr 3: 184.05 – 184.06 Mb n/a
PubMed search [1] n/a
Wikidata
View/Edit Human

5-hydroxytryptamine receptor 3C is a protein that in humans is encoded by the HTR3C gene.[2][2][3] The protein encoded by this gene is a subunit of the 5-HT3 receptor.[3]

References

  1. ↑ "Human PubMed Reference:".
  2. 1 2 Niesler B, Frank B, Kapeller J, Rappold GA (Jun 2003). "Cloning, physical mapping and expression analysis of the human 5-HT3 serotonin receptor-like genes HTR3C, HTR3D and HTR3E". Gene. 310: 101–11. doi:10.1016/S0378-1119(03)00503-1. PMID 12801637.
  3. 1 2 Peters JA, Kelley SP, Dunlop JI, Kirkness EF, Hales TG, Lambert JJ (May 2004). "The 5-hydroxytryptamine type 3 (5-HT3) receptor reveals a novel determinant of single-channel conductance". Biochem Soc Trans. 32 (Pt3): 547–52. doi:10.1042/BST0320547. PMID 15157181.

Further reading

  • Karnovsky AM, Gotow LF, McKinley DD, et al. (2003). "A cluster of novel serotonin receptor 3-like genes on human chromosome 3.". Gene. 319: 137–48. doi:10.1016/S0378-1119(03)00803-5. PMID 14597179. 
  • Fasching PA, Kollmannsberger B, Strissel PL, et al. (2008). "Polymorphisms in the novel serotonin receptor subunit gene HTR3C show different risks for acute chemotherapy-induced vomiting after anthracycline chemotherapy.". J. Cancer Res. Clin. Oncol. 134 (10): 1079–86. doi:10.1007/s00432-008-0387-1. PMID 18389280. 
  • Ward MB, Kotasek D, McKinnon RA (2008). "Investigation of HTR3C mutations for association with 5HT(3) receptor antagonist anti-emetic efficacy.". Pharmacogenomics. 9 (8): 1027–33. doi:10.2217/14622416.9.8.1027. PMID 18681779. 

External links


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