HLA-B42

major histocompatibility complex (human), class I, B42
Alleles B*4201
B*4202
Structure (See HLA-B)
Symbol(s) HLA-B
EBI-HLA B*4201
EBI-HLA B*4202
Locus chr.6 6p21.31

HLA-B42 (B42) is an HLA-B serotype. The serotype identifies the HLA-B*4201 and *4202 gene products.[1] HLA-B*4201 is common in Central Africa. (For terminology help see: HLA-serotype tutorial)

Serotype

B42 serotype recognition of Some HLA B*42 allele-group gene products[2]
B*42 B42 other Sample
allele % % size (N)
4201 93 2 1015
4202 95 80

Serological typing for B*4201 and B*4202 is relatively efficient.

B*4201 allele frequencies

HLA B*4201 frequencies
freq
ref. Population (%)
[3] Zambia Lusaka14.8
[3] Mali Bandiagara13.8
[3] Burkina Faso Mossi13.2
[3] South African Natal Zulu12.0
[3] Burkina Faso Rimaibe9.6
[3] South Africa Tswana8.5
[3] Kenya Luo7.7
[3] Kenya 7.3
[3] Kenya Nandi6.9
[3] Zimbabwe Harare Shona6.9
[3] Saudi Arabia5.6
[3] Cameroon Yaounde4.9
[3] Cameroon Beti4.0
[3] Cameroon Bamileke3.9
[3] Cameroon Sawa3.8
[3] Ivory Coast Akan Adiopodoume3.4
[3] Israel Gaza Palestinians2.4
[3] India North Delhi2.2
[3] Senegal Niokholo Mandenka1.6
[3] Mbenzele Pygmy (C. Afr. Rep.)1.5
[3] Iran Baloch1.5
[3] Pakistan Baloch1.5
[3] Sudanese1.5
[3] Tunisia1.5
[3] Pakistan Brahui1.4
[3] Cameroon Bamileke1.3
[3] Oman1.3
[3] Sudanese1.3
[3] Tunisia Tunis1.1
[3] Zimbabwe Harare Shona1.1
[3] Cameroon Bakola Pygmy1.0
[3] Pakistan Pathan1.0
[3] Portugal Centre1.0
[3] Saudi Arabia Guraiat and Hail1.0
[3] Morocco Casablanca0.9
[3] Senegal Dakar0.9
[3] Uganda Kampala0.9
[3] Cape Verde Southeastern Islands0.8
[3] Guinea Bissau0.8
[3] United Arab Emerates0.8
[3] Morocco Nador Metalsa Class I0.7
[3] Pakistan Karachi Parsi0.6
[3] Spain Majorca0.6
[3] China Yunnan Han pop20.5
[3] England Newcastle0.5
[3] Israel Arab Druse0.5
[3] Israel Jews0.5
[3] Italy Rome0.5
[3] Guadalajara Mestizos (2) (Mexico) 0.5
[3] Morocco0.5
[3] Pakistan Sindhi0.5
[3] Senegal Niokholo Mandenka0.5
[3] Singapore Riau Malay0.5

References

  1. ↑ Marsh SG, Albert ED, Bodmer WF, et al. (2005). "Nomenclature for factors of the HLA system, 2004". Tissue Antigens. 65 (4): 301–69. doi:10.1111/j.1399-0039.2005.00379.x. PMID 15787720.
  2. ↑ derived from IMGT/HLA
  3. 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 Middleton D, Menchaca L, Rood H, Komerofsky R (2003). "New allele frequency database: http://www.allelefrequencies.net". Tissue Antigens. 61 (5): 403–7. doi:10.1034/j.1399-0039.2003.00062.x. PMID 12753660. External link in |title= (help)
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