# General Leibniz rule

For other uses, see Leibniz's rule (disambiguation).

In calculus, the general Leibniz rule,[1] named after Gottfried Leibniz, generalizes the product rule (which is also known as "Leibniz's rule"). It states that if u and v are n-times differentiable functions, then product uv is also n-times differentiable and its nth derivative is given by

where is the binomial coefficient.

This can be proved by using the product rule and mathematical induction.

In case :

## More than two factors

The formula can be generalized to the product of m differentiable functions f1,...,fm.

where the sum extends over all m-tuples (k1,...,km) of non-negative integers with and

are the multinomial coefficients. This is akin to the multinomial formula from algebra.

## Multivariable calculus

With the multi-index notation for partial derivatives of functions of several variables, the Leibniz rule states more generally:

This formula can be used to derive a formula that computes the symbol of the composition of differential operators. In fact, let P and Q be differential operators (with coefficients that are differentiable sufficiently many times) and . Since R is also a differential operator, the symbol of R is given by:

A direct computation now gives:

This formula is usually known as the Leibniz formula. It is used to define the composition in the space of symbols, thereby inducing the ring structure.