Gabriel Bertrand
| Gabriel Bertrand | |
|---|---|
| Born |
May 17, 1867 Paris |
| Died |
June 20, 1962 (aged 95) Paris |
| Nationality | French |
| Institutions | Institut Pasteur |
| Doctoral advisor | Émile Duclaux |
| Other academic advisors | Edmond Frémy |
| Known for |
concepts of oxidase and trace elements Bertrand's rule |
Gabriel Bertrand (born 17 May 1867 in Paris, died 20 June 1962 in Paris) was a French pharmacologist, biochemist and bacteriologist.
Bertrand introduced into biochemistry both the term “oxidase” and the concept of trace elements.
The laccase, a polyphenol oxidase and an enzyme oxidating urishiol and laccol obtained from the lacquer tree, was first studied by Gabriel Bertrand[1] in 1894.[2]
Bertrand's rule is the fact that the dose–response curve for many micronutrients is non-monotonic, having an initial stage of increasing benefits with increased intake, followed by increasing costs as excesses become toxic.[3]
In 1894, with Césaire Phisalix, he developed an antivenom for use against snake bites.[4]
Bertrand was made a member of the Académie Nationale de Médecine in 1931. In 1932 he became foreign member of the Royal Netherlands Academy of Arts and Sciences.[5]
References
- ↑ Gabriel Bertrand on isimabomba.free.fr (French)
- ↑ Science and civilisation in China: Chemistry and chemical ..., Volume 5, Part 4 By Joseph Needham, Ping-Yü Ho, Gwei-Djen Lu and Nathan Sivin, p. 209
- ↑ Does Bertrand's rule apply to macronutrients? D Raubenheimer, K.P Lee and S.J Simpson, Proc Biol Sci. 2005 November 22; 272(1579): 2429–2434, doi:10.1098/rspb.2005.3271
- ↑ Le Musee Pasteur Césaire et Marie PHISALIX, deux chercheurs comtois
- ↑ "G. Bertrand (1867 - 1962)". Royal Netherlands Academy of Arts and Sciences. Retrieved 20 July 2015.