SULT1E1

SULT1E1
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
Aliases SULT1E1, EST, EST-1, ST1E1, STE, sulfotransferase family 1E member 1
External IDs MGI: 98431 HomoloGene: 101388 GeneCards: SULT1E1
RNA expression pattern
More reference expression data
Orthologs
Species Human Mouse
Entrez

6783

20860

Ensembl

ENSG00000109193

ENSMUSG00000029272

UniProt

P49888

P49891

RefSeq (mRNA)

NM_005420

NM_023135

RefSeq (protein)

NP_005411.1

n/a

Location (UCSC) Chr 4: 69.81 – 69.86 Mb Chr 5: 87.58 – 87.59 Mb
PubMed search [1] [2]
Wikidata
View/Edit HumanView/Edit Mouse

Estrogen sulfotransferase is an enzyme that in humans is encoded by the SULT1E1 gene.[3][4]

Sulfotransferase enzymes catalyze the sulfate conjugation of many hormones, neurotransmitters, drugs, and xenobiotic compounds. These cytosolic enzymes are different in their tissue distributions and substrate specificities. The gene structure (number and length of exons) is similar among family members. This gene encodes a protein that transfers a sulfo moiety to and from estrone, which may control levels of estrogen receptors.[4]

See also

References

  1. "Human PubMed Reference:".
  2. "Mouse PubMed Reference:".
  3. Bernier F, Leblanc G, Labrie F, Luu-The V (Dec 1994). "Structure of human estrogen and aryl sulfotransferase gene. Two mRNA species issued from a single gene". J Biol Chem. 269 (45): 28200–5. PMID 7961757.
  4. 1 2 "Entrez Gene: SULT1E1 sulfotransferase family 1E, estrogen-preferring, member 1".

Further reading


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