Constantine Angelos (Greek: Κωνσταντίνος Άγγελος; fl. 1122–66) was a Byzantine admiral and panhypersebastos, of Philadelphia, the commander of the Imperial Fleet in Sicily, who married Theodora Komnene (born 1097) in 1122, the youngest daughter of Emperor Alexios I Komnenos and Irene Doukaina. According to the near-contemporary Niketas Choniates, Constantine was brave, skilled and handsome, but of lowly origin. He was the son of one Manolis Angelos from Philadelphia and had three brothers: Nikolaos Angelos, Michael Angelos and Ioannes Angelos, a military leader in Italy.
- John Doukas (ca. 1125/27 – ca. 1200), had several children by one or two marriages, and a bastard son. The latter, Michael I Komnenos Doukas, would go on to found the Despotate of Epirus, and was succeeded by his half-brothers.
- Alexios Komnenos Angelos, married and fathered one son.
- Andronikos Doukas Angelos (died after 1185), Byzantine general in Asia Minor, married Euphrosyne Kastamonitissa, by whom he had nine children including emperors Alexios III Angelos and Isaac II Angelos.
- Isaac Angelos, military governor of Cilicia
- Maria Angelina, married Constantine Kamytzes, by whom she had one daughter.
- Eudokia Angelina, married Basil Tsykandeles
- Zoe Angelina, married Andronikos Synadenos