Chlorphenoxamine

Chlorphenoxamine
Clinical data
AHFS/Drugs.com International Drug Names
Routes of
administration
Oral, topical
ATC code D04AA34 (WHO) R06AA06 (WHO)
Pharmacokinetic data
Bioavailability Well absorbed
Metabolism Likely hepatic
Excretion Renal
Identifiers
CAS Number 77-38-3 YesY 562-09-4
PubChem (CID) 6475
DrugBank DB09007 N
ChemSpider 6230 YesY
UNII 3UVD77BP8R YesY
KEGG D07198 YesY
ChEMBL CHEMBL2110774 N
ECHA InfoCard 100.115.538
Chemical and physical data
Formula C18H22ClNO
Molar mass 303.826 g/mol
3D model (Jmol) Interactive image
 NYesY (what is this?)  (verify)

Chlorphenoxamine (Phenoxene) is an antihistamine and anticholinergic used as an antipruritic[1] and antiparkinsonian[2] agent. It is an analog of diphenhydramine.[3]

References

  1. Bazex, A.; Dupre, A.; Christol, B. (1963). "Trial treatment of urticaria with chlorphenoxamine". Clinique (Paris, France). 58: 447–450. PMID 13967113.
  2. Uldall, P. R.; Walton, J. N.; Newell, D. J. (1961). "Chlorphenoxamine hydrochloride in parkinsonism. A controlled trial". British Medical Journal. 1 (5240): 1649–1652. doi:10.1136/bmj.1.5240.1649. PMC 1954253Freely accessible. PMID 13779077.
  3. H. Arnold, N. Brock, E. Kuhas, and D. Lorenz, Arzneimittel Forsch., 4, 189 (1954).


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