Cellosaurus

Cellosaurus
Content
Description Cellosaurus: a knowledge resource on cell lines
Data types
captured		 Cell lines
Organisms Vertebrate, Insect, Tick
Contact
Research center Swiss Institute of Bioinformatics
Laboratory CALIPHO
Authors Amos_Bairoch
Access
Data format Flat file database and OBO
Website web.expasy.org/cellosaurus/
Tools
Web Search
Miscellaneous
License Creative Commons Attribution-NoDerivs
Versioning Yes
Data release
frequency		 4 to 6 releases per year
Curation policy Yes - manual
Bookmarkable
entities		 Yes - individual cell line entries

Cellosaurus is an on-line knowledge resource on cell lines. Its scope includes immortalised cell lines, naturally immortal cell lines (example: embryonic stem cells) and finite life cell lines when those are distributed and used widely. The Cellosaurus provides a wealth of manually curated information; for each cell line it lists a recommended name, synonyms and the species of origin. Other types of information include standardised disease terminology (for cancer or genetic disorder cell lines), the transformant used to immortalise a cell line, transfected or knocked-out genes, web links, publication references and cross-references to more than 50 different databases, cell collections and other relevant resources.

Since many cell lines used in research have been misidentified or contaminated, the Cellosaurus keeps track of problematic cell lines, including all those listed in the International Cell Line Authentication Committee (ICLAC) [1] tables.

For human cell lines, it provides short tandem repeat (STR) profile information, which is critical to the important process of cell line authentication.

It is developed by Amos Bairoch at the CALIPHO group [2] of the Swiss Institute of Bioinformatics (SIB).

References

  1. ↑ http://iclac.org/wp-content/uploads/Cross-Contaminations-v7_2.pdf
  2. ↑ CALIPHO group, on the web site of the SIB

External links

This article is issued from Wikipedia - version of the 11/2/2016. The text is available under the Creative Commons Attribution/Share Alike but additional terms may apply for the media files.