Brutieridin

Brutieridin
Properties
C34H42O19
Molar mass 754.69 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references

Brutieridin is a flavanone glycoside. Brutieridin was discovered in bergamot orange juice and exhibits statin-like properties[1][2] so the juice seems to have hypolipidemic (lipid-lowering) activity.[1][3][4][5]

References

  1. 1 2 Di Donna, Leonardo; De Luca, Giuseppina; Mazzotti, Fabio; Napoli, Anna; Salerno, Raffaele; Taverna, Domenico; Sindona, Giovanni (2009). "Statin-like Principles of Bergamot Fruit: Isolation of 3-Hydroxymethylglutaryl Flavonoid Glycosides". Journal of Natural Products. 72 (7): 1352–1354. doi:10.1021/np900096w. PMID 19572741.
  2. Di Donna, Leonardo; Gallucci, Giselda; Malaj, Naim; Romano, Elvira; Tagarelli, Antonio; Sindona, Giovanni (2011). "Recycling of industrial essential oil waste: Brutieridin and Melitidin, two anticholesterolaemic active principles from bergamot albedo". Food Chemistry. 125 (2): 438–441. doi:10.1016/j.foodchem.2010.09.025. ISSN 0308-8146.
  3. Natalizia Miceli; M. R. Mondello; M. T. Monforte; V. Sdrafkakis; P. Dugo; M. L. Crupi; M. F. Taviano; R. De Pasquale & A. Trovato (2007). "Hypolipidemic Effects of Citrus bergamia Risso et Poiteau Juice in Rats Fed a Hypercholesterolemic Diet". J. Agric. Food Chem. 55 (27): 10671–10677. doi:10.1021/jf071772i.
  4. Monica Leopoldini; N. Malaj; M. Toscano; G. Sindona & N. Russo (2010). "On the Inhibitor Effects of Bergamot Juice Flavonoids Binding to the 3-Hydroxy-3-methylglutaryl-CoA Reductase (HMGR) Enzyme". J. Agric. Food Chem. 58 (19): 10768–10773. doi:10.1021/jf102576j.
  5. Vincenzo Mollace; I. Sacco; E. Janda; C. Malara; D. Ventrice; C. Colica; V. Visalli; S. Muscoli; S. Ragusa; C. Muscoli; D. Rotirotia; F. Romeo (2011). "Hypolipemic and hypoglycaemic activity of bergamot polyphenols: From animal models to human studies". Fitoterapia. 82 (3): 309–316. doi:10.1016/j.fitote.2010.10.014. PMID 21056640. PDF

Bibliography

See also


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