The bisphenols (pronounced /ˈbɪs.f.nɒl/) are a group of chemical compounds with two hydroxyphenyl functionalities. Most of them are based on diphenylmethane. The exceptions are bisphenol S, P, and M. "Bisphenol" is a common name; the letter following refers to one of the reactants. Bisphenol A is the most popular representative of this group, often simply called "bisphenol."


Structural formula Name CAS Reactants Systematic name
Bisphenol A 80-05-7 Phenol Acetone 2,2-Bis(4-hydroxyphenyl)propane
Bisphenol AP 1571-75-1 Phenol Acetophenone 1,1-Bis(4-hydroxyphenyl)-1-phenyl-ethane
Bisphenol AF 1478-61-1 Phenol Hexafluoroacetone 2,2-Bis(4-hydroxyphenyl)hexafluoropropane
Bisphenol B 77-40-7 Phenol Butanone 2,2-Bis(4-hydroxyphenyl)butane
Bisphenol BP 1844-01-5 Phenol Benzophenone Bis-(4-hydroxyphenyl)diphenylmethane
Bisphenol C 79-97-0 Cresol Acetone 2,2-Bis(3-methyl-4-hydroxyphenyl)propane
Bisphenol C 2 14868-03-2 Phenol Dichloromethane Bis(4-hydroxyphenyl)-2,2-dichlorethylene
Bisphenol E 2081-08-5 Phenol Acetaldehyde 1,1-Bis(4-hydroxyphenyl)ethane
Bisphenol F 87139-40-0 Phenol Formaldehyde Bis(4-hydroxyphenyl)methane
Bisphenol G 127-54-8 2-Isopropylphenol Acetone 2,2-Bis(4-hydroxy-3-isopropyl-phenyl)propane
Bisphenol M 13595-25-0 1,3-Bis(2-(4-hydroxyphenyl)-2-propyl)benzene
Bisphenol S 80-09-1 Phenol Sulfur trioxide Bis(4-hydroxyphenyl)sulfone
Bisphenol P 2167-51-3 1,4-Bis(2-(4-hydroxyphenyl)-2-propyl)benzene
Bisphenol PH 24038-68-4 2-Phenylphenol Acetone 5,5’ -(1-Methylethyliden)-bis[1,1’-(bisphenyl)-2-ol]propane
Bisphenol TMC 129188-99-4 Phenol 3,3,5-Trimethylcyclohexanone 1,1-Bis(4-hydroyphenyl)-3,3,5-trimethyl-cyclohexane
Bisphenol Z 843-55-0 Phenol Cyclohexanone 1,1-Bis(4-hydroxyphenyl)-cyclohexane

Bisphenol A diglycidyl ether (BADGE) is another bisphenol derivative, along with EPI-001.

Health effects

Bisphenols A (BPA) and S (BPS) are endocrine disruptors.[1][2] Due to its high production volumes BPA has been characterised as a "pseudo-persistent" chemical,[3] leading to its spreading and potential accumulation in a variety of environmental matrices.

Prevention measures

These products tend to release from the material when heated; as a precaution, it is recommended for the consumer:


  1. "BPA-Free Plastic Containers May Be Just as Hazardous". Scientific American. Retrieved 8 August 2015.
  2. "Bisphenol A (BPA) & Bisphenol S (BPS)". Retrieved 8 August 2015.
  3. Pivnenko, K.; Pedersen, G. A.; Eriksson, E.; Astrup, T. F. (2015-10-01). "Bisphenol A and its structural analogues in household waste paper". Waste Management. 44: 39–47. doi:10.1016/j.wasman.2015.07.017. PMID 26194879.
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