Bis(2-ethylhexyl) adipate

Bis(2-ethylhexyl) adipate
IUPAC name
Bis(2-ethylhexyl) hexanedioate
Other names
DEHA; Diisooctyl adipate;
Di(2-ethylhexyl) adipate
103-23-1 YesY
3D model (Jmol) Interactive image
Abbreviations DEHA
ChemSpider 7358 YesY
ECHA InfoCard 100.002.810
KEGG C14240 YesY
PubChem 7641
Molar mass 370.57 g·mol−1
Appearance colourless oily liquid
Density 0.93 g/cm3
Melting point −67.8 °C (−90.0 °F; 205.3 K)
Boiling point 417 °C (783 °F; 690 K)
Vapor pressure 2.6 mm Hg at 200 °C
Safety data sheet Oxford University
Flash point 196 °C (385 °F; 469 K)
377 °C (711 °F; 650 K)
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Infobox references

Bis(2-ethylhexyl) adipate or DEHA is a plasticizer. DEHA is an ester of 2-ethylhexanol and adipic acid. Its chemical formula is C22H42O4.

DEHA is sometimes called "dioctyl adipate", incorrectly. Other names include diisooctyl adipate and di(2-ethylhexyl) adipate.


DEHA is used as a functional hydraulic fluid, and a component of aircraft lubricants. It is sometimes also used as an ingredient in PVC-based plastic wrap.


DEHA has been demonstrated to induce liver adenomas and carcinomas in mice but not in rats. According to the International Agency for Research on Cancer (IARC), it is "not classifiable as to its carcinogenicity to humans (Group 3),"[1] suggesting inadequate evidence of human carcinogenicity.[2] While once on a U.S. Environmental Protection Agency list of toxic chemicals under the Emergency Planning and Community Right-to-Know Act, it has been removed because it "cannot be reasonably anticipated to cause [...] irreversible chronic health effects."[3]


  1. IARC - Summaries & Evaluations: DI(2-ETHYLHEXYL) ADIPATE, 77, 2000, p. 149, retrieved 2008-12-20
  2. Inchem Preamble Evaluation, 1-5-1999, retrieved 2008-12-20 Check date values in: |date= (help)
  3. Bottle Royale, retrieved 2008-12-20
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