Benzhydrocodone

Benzhydrocodone
Clinical data
Routes of
administration
Oral
Identifiers
Synonyms KP201
CAS Number 1259440-61-3
ChemSpider 31484780
Chemical and physical data
Formula C25H25NO4
Molar mass 403.470
3D model (Jmol) Interactive image

Benzhydrocodone (INN) (contracted from benzoate-hydrocodone) is a opioid prodrug of the morphinan class. Its chemical structure consists of hydrocodone coupled with benzoic acid. Benzhydrocodone itself is inactive and acts as a prodrug to hydrocodone upon cleavage of the benzoate portion of the molecule.[1]

It is designed to be an opioid analgesic with a low chance of recreational use.[2]

Created by a biopharmaceutical company in Coralville, Iowa. President and CEO, Travis Mickle, believes the molecular-based approach to abuse-detterent may be more effective than many formulation-based approaches.[3]

References

  1. KemPharm, Inc. (June 11, 2013). "KemPharm, Inc. Receives Patent from the USPTO for Novel Pain Drug Candidate, KP201" (Press release). North Liberty, Iowa: PR Newswire. Retrieved February 8, 2015.
  2. Lavitt, John (June 12, 2014). "New Abuse-Resistant Opioid Receives $60 Million Backing". http://thefix.com/. The Fix. Retrieved February 8, 2015. External link in |website= (help)
  3. "KP201/APAP". http://www.kempharm.com/. Retrieved April 20, 2015. External link in |website= (help)



This article is issued from Wikipedia - version of the 4/2/2016. The text is available under the Creative Commons Attribution/Share Alike but additional terms may apply for the media files.