BAPTA
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| Names | |
|---|---|
| IUPAC name
1,2-bis(o-aminophenoxy)ethane-N,N,N′,N′-tetraacetic acid | |
| Identifiers | |
85233-19-8  | |
| 3D model (Jmol) | Interactive image |
| ChEBI | CHEBI:60888  |
| ChemSpider | 94562 |
| ECHA InfoCard | 100.157.377 |
| PubChem | 104751 |
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| Properties | |
| C22H24N2O10 | |
| Molar mass | 476.433 |
| Density | 1.494 g/cm3 |
| Melting point | 177 to 179 °C (351 to 354 °F; 450 to 452 K) |
| Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). | |
| verify (what is ?) | |
| Infobox references | |
BAPTA (1,2-bis(o-aminophenoxy)ethane-N,N,N′,N′-tetraacetic acid) is a calcium-specific aminopolycarboxylic acid. The presence of four carboxylic acid functional groups makes possible the binding of two calcium ions. The extensive flexibility of the carboxylate ligands is critical to the coordination of calcium and other metal ions.
There is a range of reported values for the dissociation constant of BAPTA, though 0.2 µM appears consistently.[1] The rate constant for calcium binding is 500 µM−1 s−1.[1]
See also
References
- 1 2 Ricci AJ, Wu YC, Fettiplace R (15 October 1998). "The endogenous calcium buffer and the time course of transducer adaptation in auditory hair cells.". The Journal of Neuroscience. 18 (20): 8261–77. PMID 9763471.
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