Alternariol

Alternariol
Names
IUPAC name
3,7,9-Trihydroxy-1-methyl-6H-benzo[c]chromen-6-one
Identifiers
641-38-3 YesY
3D model (Jmol) Interactive image
Interactive image
ChEBI CHEBI:64983 N
ChEMBL ChEMBL519982 YesY
ChemSpider 4514301 YesY
ECHA InfoCard 100.164.145
KEGG C16838 YesY
PubChem 5359485
UNII KN9L4260JW YesY
Properties
C14H10O5
Molar mass 258.23 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
N verify (what is YesYN ?)
Infobox references

Alternariol is a toxic metabolite of Alternaria fungi.[1] It is an important contaminant in cereals and fruits.[2] Alternariol exhibits antifungal and phytotoxic activity. It is reported to inhibit cholinesterase enzymes.[3] It is also a mycoestrogen.

References

  1. Davis VM, Stack ME (1 October 1994). "Evaluation of alternariol and alternariol methyl ether for mutagenic activity in Salmonella typhimurium". Appl. Environ. Microbiol. 60 (10): 3901–2. PMC 201908Freely accessible. PMID 7986060.
  2. Brugger EM, Wagner J, Schumacher DM, et al. (2006). "Mutagenicity of the mycotoxin alternariol in cultured mammalian cells". Toxicol. Lett. 164 (3): 221–30. doi:10.1016/j.toxlet.2006.01.001. PMID 16464542.
  3. Alternariol product page from Fermentek



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