ATF7

ATF7
Identifiers
Aliases ATF7, ATFA, activating transcription factor 7
External IDs MGI: 2443472 HomoloGene: 4994 GeneCards: ATF7
RNA expression pattern
More reference expression data
Orthologs
Species Human Mouse
Entrez

11016

223922

Ensembl

ENSG00000170653

ENSMUSG00000099083

UniProt

P17544

Q8R0S1

RefSeq (mRNA)

NM_001130059
NM_001130060
NM_001206682
NM_001206683
NM_006856

NM_146065
NM_001310066
NM_001310067
NM_001310070

RefSeq (protein)

NP_001123532.1
NP_001193611.1
NP_001193612.1
NP_006847.1

n/a

Location (UCSC) Chr 12: 53.51 – 53.63 Mb Chr 15: 102.53 – 102.63 Mb
PubMed search [1] [2]
Wikidata
View/Edit HumanView/Edit Mouse

Cyclic AMP-dependent transcription factor ATF-7 is a protein that in humans is encoded by the ATF7 gene.[3][4][5]

Homonym

In 2001, Peters et al. published a paper showing that ATF-7, a Novel bZIP Protein, interacts with PTP4A1.[4] This ATF-7 is actually ATF5 and not ATF7, as noted by the authors at the end of their paper ("Note Added in Proof—While this manuscript was under review, sequences for mouse and human ATF-5 were deposited in GenBankTM. It appears that ATF-7 and ATF-5 are likely to be the same protein. In addition, an unrelated sequence named ATF7 has also been deposited in GenBankTM. In order to avoid confusion, future work on the protein described in this publication will likely refer to it as either ATF-5 or ATF-5/7.")[4]

References

  1. "Human PubMed Reference:".
  2. "Mouse PubMed Reference:".
  3. Gaire M, Chatton B, Kedinger C (Aug 1990). "Isolation and characterization of two novel, closely related ATF cDNA clones from HeLa cells". Nucleic Acids Res. 18 (12): 3467–73. doi:10.1093/nar/18.12.3467. PMC 330998Freely accessible. PMID 1694576.
  4. 1 2 3 Peters CS, Liang X, Li S, Kannan S, Peng Y, Taub R, Diamond RH (Apr 2001). "ATF-7, a novel bZIP protein, interacts with the PRL-1 protein-tyrosine phosphatase". J Biol Chem. 276 (17): 13718–26. doi:10.1074/jbc.M011562200. PMID 11278933.
  5. "Entrez Gene: ATF7 activating transcription factor 7".

Further reading

External links

This article incorporates text from the United States National Library of Medicine, which is in the public domain.


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