2,8-Dihydroxyadenine

2,8-Dihydroxyadenine
Names

IUPAC name 6-Amino-7,9-dihydro-1H-purine-2,8-dione
Identifiers
CAS Number	30377-37-8^N
3D model (Jmol)	Interactive image
ChemSpider	83302^Y
ECHA InfoCard	100.045.584
MeSH	2,8-dihydroxyadenine
PubChem	92268
InChI InChI=1S/C5H5N5O2/c6-2-1-3(9-4(11)7-1)10-5(12)8-2/h(H5,6,7,8,9,10,11,12)^Y Key: XFBOJHLYDJZYSP-UHFFFAOYSA-N^Y InChI=1/C5H5N5O2/c6-2-1-3(9-4(11)7-1)10-5(12)8-2/h(H5,6,7,8,9,10,11,12) Key: XFBOJHLYDJZYSP-UHFFFAOYAF
SMILES O=C2N/C/1=N/C(=O)N\C(=C\1N2)N
Properties
Chemical formula	C₅H₅N₅O₂
Molar mass	167.126
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
N verify (what is ^YN ?)
Infobox references

2,8-Dihydroxyadenine is a derivative of adenine which accumulates in 2,8 dihydroxy-adenine urolithiasis.

References

Diculescu, VC; Piedade, JA; Oliveira-Brett, AM (2007). "Electrochemical behaviour of 2,8-dihydroxyadenine at a glassy carbon electrode". Bioelectrochemistry. 70 (1): 141–6. doi:10.1016/j.bioelechem.2006.03.015. PMID 16713382.
Taniguchi A, Tsuchida S, Kuno S, Mita M, Machida T, Ioritani N, Terai C, Yamanaka H, Kamatani N (2004). "Identification of two novel mutations in adenine phosphoribosyltransferase gene in patients with 2,8-dihydroxyadenine urolithiasis". Nucleosides Nucleotides Nucleic Acids. 23 (8–9): 1141–5. doi:10.1081/NCN-200027393. PMID 15571218.
Wilkinson H, Samuell C, Stower M (2004). "2,8-Dihydroxyadenine renal stones in a 41-year-old man". Ann Clin Biochem. 41 (Pt 2): 160–1. doi:10.1258/000456304322880087. PMID 15025810.

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